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Showing 1 to 12 of 59 entries
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WITHDRAWN:C677T Methylenetetrahydrofolate reductase gene polymorphism in schizophrenia and bipolar disorder.

Psychiatric genetics

El-Hadidy MA, Abdeen HM, Abd El-Aziz SM, Al-Harrass M.
PMID: 24276736
Psychiatr Genet. 2013 Nov 22; doi: 10.1097/YPG.0000000000000020. Epub 2013 Nov 22.

Ahead of Print article withdrawn by publisher.

Psychiatric Genetics, where we have been and where we are going.

Psychiatric genetics

McQuillin A.
PMID: 31464993
Psychiatr Genet. 2019 Oct;29(5):131. doi: 10.1097/YPG.0000000000000233.

No abstract available.

Evaluation of hsa-let-7d-5p, hsa-let-7g-5p and hsa-miR-15b-5p plasma levels in patients with Alzheimer's disease.

Psychiatric genetics

Poursaei E, Abolghasemi M, Bornehdeli S, Shanehbandi D, Asadi M, Sadeghzadeh M, Rahmanpour D, Sadeh RN.
PMID: 34955516
Psychiatr Genet. 2022 Feb 01;32(1):25-29. doi: 10.1097/YPG.0000000000000303.

BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disorder MicroRNAs (miRNAs) may be promising diagnostic biomarkers for AD. Previous evidence shows that miR-15b-5p, hsa-let7g-5p and hsa-let7d-5p might confer potential blood biomarkers for timely diagnosis of AD. Therefore, in this...

Evaluation of hsa-let-7d-5p, hsa-let-7g-5p and hsa-miR-15b-5p plasma levels in patients with Alzheimer's disease.

Psychiatric genetics

Poursaei E, Abolghasemi M, Bornehdeli S, Shanehbandi D, Asadi M, Sadeghzadeh M, Rahmanpour D, Sadeh RN.
PMID: 34955516
Psychiatr Genet. 2022 Feb 01;32(1):25-29. doi: 10.1097/YPG.0000000000000303.

BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disorder MicroRNAs (miRNAs) may be promising diagnostic biomarkers for AD. Previous evidence shows that miR-15b-5p, hsa-let7g-5p and hsa-let7d-5p might confer potential blood biomarkers for timely diagnosis of AD. Therefore, in this...

A case of White-Sutton syndrome arising from a maternally-inherited mutation in POGZ.

Psychiatric genetics

Liu S, Yan Z, Huang Y, Zheng W, Deng Y, Zou Y, Xie H.
PMID: 34133408
Psychiatr Genet. 2021 Aug 01;31(4):135-139. doi: 10.1097/YPG.0000000000000288.

POGZ is located on chromosome 1q21.3, encoding a pogo transposable element-derived protein with a zinc finger cluster. White-Sutton syndrome (WHSUS, OMIM:616364) is a genetic disorder resulting from de novo heterozygous pathogenic variants in POGZ, which manifests as intellectual disability,...

CYP2C19 polymorphisms are associated with severity of depression at initial evaluation and after the treatment independently of the prescribed medications: 4 weeks prospective study.

Psychiatric genetics

Strumila R, Lengvenyte A, Ambrozaityte L, Balkeliene D, Utkus A, Dlugauskas E.
PMID: 34133409
Psychiatr Genet. 2021 Oct 01;31(5):177-185. doi: 10.1097/YPG.0000000000000287.

BACKGROUND: The cytochrome P-450 2C19 (CYP2C19) enzyme is involved in the metabolism of numerous antidepressants. It also metabolises some endogenous substrates, which could also confer to vulnerability. We aimed to establish whether the severity of depression and treatment response...

Mediating effect of genome-wide DNA methylation on suicidal ideation induced by perceived stress.

Psychiatric genetics

Dada O, Adanty C, Dai N, Zai C, Gerretsen P, Graff A, de Luca V.
PMID: 34050117
Psychiatr Genet. 2021 Oct 01;31(5):168-176. doi: 10.1097/YPG.0000000000000281.

Stress is an important risk factor for suicidal ideation, but the mechanisms that link stress, suicidal ideation and neurobiology remain unclear. Epigenetic mechanisms are involved in both vulnerability to suicidal behavior and stress. This is a pilot study of...

Analysis of 200 000 exome-sequenced UK Biobank subjects fails to identify genes influencing probability of developing a mood disorder resulting in psychiatric referral.

Psychiatric genetics

Curtis D.
PMID: 34050118
Psychiatr Genet. 2021 Oct 01;31(5):194-198. doi: 10.1097/YPG.0000000000000282.

BACKGROUND: Depression is moderately heritable but there is no common genetic variant which has a major effect on susceptibility. A previous analysis of 50 000 exome-sequenced subjects failed to implicate any genes or sets of genes in which rare...

Effects of vitamin D-related gene polymorphisms on attempted suicide.

Psychiatric genetics

Wei YX, Liu BP, Qiu HM, Zhang JY, Wang XT, Jia CX.
PMID: 34412081
Psychiatr Genet. 2021 Dec 01;31(6):230-238. doi: 10.1097/YPG.0000000000000295.

OBJECTIVE: Emerging evidence suggests that vitamin D might protect from attempted suicide. The study aimed to investigate the associations between single-nucleotide polymorphisms (SNPs) related to vitamin D levels identified in a large genome-wide association study and attempted suicide in...

The OPRD1 rs678849 variant influences outcome of disulfiram treatment for cocaine dependency in methadone-maintained patients.

Psychiatric genetics

Thomas PS, Nielsen EM, Spellicy CJ, Harding MJ, Ye A, Patriquin M, Hamon SC, Kosten TR, Nielsen DA.
PMID: 33953123
Psychiatr Genet. 2021 Jun 01;31(3):88-94. doi: 10.1097/YPG.0000000000000279.

OBJECTIVE: Prior research demonstrated that the δ-opioid receptor (OPRD1) rs678849 variant influences opioid use in African Americans treated with methadone. We examined whether this variant moderated cocaine and opioid use in our clinical cohort of methadone and disulfiram treated...

Exploring the utility of current polygenic scores in capturing resilience.

Psychiatric genetics

Bucknor BA, Derringer J, Maciver D, Rutherford M, Arakelyan S, Kramer JM.
PMID: 34538866
Psychiatr Genet. 2021 Sep 15; doi: 10.1097/YPG.0000000000000300. Epub 2021 Sep 15.

Although resilience has been identified to be moderately heritable, little is known about the genetic variants involved. While there has not yet been a robust genome-wide association study (GWAS) of resilience, existing GWAS of related phenotypes may provide a...

Two siblings with autism spectrum disorder and two different genetic abnormalities: paternal 16p11.2 microdeletion and maternal 17q12 microduplication.

Psychiatric genetics

Erbay MF, Karayağmurlu A, Ravneberg B.
PMID: 34538867
Psychiatr Genet. 2021 Dec 01;31(6):246-249. doi: 10.1097/YPG.0000000000000301.

Etiopathogenesis of autism spectrum disorder (ASD) is highly heterogeneous. Genetic factors play a major role in the etiology of ASD, and 16p11.2 microdeletion is one of the best-known genetic abnormalities thought to be strongly linked to ASD. Conversely, 17q12...

Showing 1 to 12 of 59 entries